HPLC purity
Reverse-phase HPLC with UV detection; purity target reported per lot with related-substance reporting on request.
Vial illustrations reflect supplied lyophilized format. Distribution scope and destination market confirmed before invoicing.
| Compound | FOXO4-DRI |
|---|---|
| CAS number | 2460055-10-9 |
| Molecular formula | C228H388N86O64 |
| Molecular weight | 5358.15 g/mol (free base) |
| Sequence | LTLRKEPASEIAQSILEAYSQNGWANRRSGGKRPPPRRRQRRKKRG (46 residues, all-D retro-inverso) |
| Form | Lyophilized powder, glass vial |
| Purity target | ≥ 99% by HPLC |
| Vial formats | 2mg / 10mg |
| Documentation | Batch-document availability confirmed by product, specification and applicable lot |
| Distribution scope | Research use, worldwide |
| Storage | Store lyophilized powder at -20 °C; ship on cold packs. After reconstitution keep at 2-8 °C and use within the validated window. Protect from light and avoid repeated freeze-thaw cycles. |
| Tier | Quantity | Lead time |
|---|---|---|
| OEM lot | 50 kits (500 vials) | 3–7 days |
| Production lot | 500–1,000 vials | 10–14 days |
| OEM repeat | 1,000+ vials | 14–18 days, scheduled |
Supplied as a research-use peptide. Every quote confirms current-batch COA, purity, destination market and buyer track before invoicing.
Overview
FOXO4-DRI is a cell-penetrating D-retro-inverso peptide built from a FOXO4 p53-binding fragment fused to a TAT-derived import sequence, placing it in the senolytic / cellular-aging research class. In published cell and animal studies it competes with endogenous FOXO4 for p53, releasing p53 to induce apoptosis preferentially in senescent cells.
Documentation
batch-document availability confirmed by product, specification and applicable lot. Distribution scope confirmed before invoicing.
Reverse-phase HPLC with UV detection; purity target reported per lot with related-substance reporting on request.
Mass spectrometry identity confirmation against the FOXO4-DRI reference profile.
Compound prefix and lot serial printed on the vial label and repeated in the document pack and carton.
FAQ
FOXO4-DRI is stocked as lyophilized powder in 2 mg and 10 mg vials, with a minimum order of 50 kits (500 vials). Larger bulk quantities and custom fills are quoted on RFQ.
For the applicable lot, Pepti confirms the available document set during RFQ review. Depending on the product and lot, the set can include a batch-specific certificate of analysis showing HPLC purity and mass-spec (MS) identity confirmation. Additional COA parameters and third-party testing can be arranged on request.
Yes. FOXO4-DRI is synthesized as an all-D-amino-acid retro-inverso construct — the residue order is reversed and built from D-amino acids — which is characteristic of this molecule and improves proteolytic stability versus a native L-peptide.
Yes. We supply bulk peptide and support private-label filling, custom vial sizing, and label/packaging for research-use brands. Regulatory positioning and compliance in the buyer's market remain the buyer's responsibility.
FOXO4-DRI is typically supplied with a ≥99% HPLC purity target. Actual purity, net-peptide content, endotoxin (only if specifically ordered and tested), and residual-solvent specifications are confirmed per lot on the COA and can be tailored on RFQ.
Related compounds
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